NPARC
This is the released version of NPARC; for the devel version, see NPARC.
Non-parametric analysis of response curves for thermal proteome profiling experiments
Bioconductor version: Release (3.23)
Perform non-parametric analysis of response curves as described by Childs, Bach, Franken et al. (2019): Non-parametric analysis of thermal proteome profiles reveals novel drug-binding proteins.
Author: Dorothee Childs, Nils Kurzawa
Maintainer: Nils Kurzawa <nilskurzawa at gmail.com>
citation("NPARC")):
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.
Installation
To install this package, start R (version "4.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("NPARC")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("NPARC")
| Analysing thermal proteome profiling data with the NPARC package | HTML | R Script |
| Reference Manual | ||
| NEWS | Text |
Details
| biocViews | Proteomics, Software |
| Version | 1.24.0 |
| In Bioconductor since | BioC 3.11 (R-4.0) (6.5 years) |
| License | GPL-3 |
| Depends | R (>= 4.0.0) |
| Imports | dplyr, tidyr, BiocParallel, broom, MASS, rlang, magrittr, stats, methods |
| System Requirements | |
| URL |
See More
| Suggests | testthat, devtools, knitr, rprojroot, rmarkdown, ggplot2, BiocStyle |
| Linking To | |
| Enhances | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | NPARC_1.24.0.tar.gz |
| Windows Binary (x86_64) | NPARC_1.24.0.zip |
| macOS Binary (big-sur-x86_64) | NPARC_1.24.0.tgz |
| macOS Binary (sonoma-arm64) | NPARC_1.24.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/NPARC |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/NPARC |
| Bioc Package Browser | https://code.bioconductor.org/browse/NPARC/ |
| Package Short Url | https://bioconductor.org/packages/NPARC/ |
| Package Downloads Report | Download Stats |