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MBECS

This is the released version of MBECS; for the devel version, see MBECS.

Evaluation and correction of batch effects in microbiome data-sets


Bioconductor version: Release (3.23)

The Microbiome Batch Effect Correction Suite (MBECS) provides a set of functions to evaluate and mitigate unwated noise due to processing in batches. To that end it incorporates a host of batch correcting algorithms (BECA) from various packages. In addition it offers a correction and reporting pipeline that provides a preliminary look at the characteristics of a data-set before and after correcting for batch effects.

Author: Michael Olbrich [aut, cre] ORCID iD ORCID: 0000-0003-2789-3382

Maintainer: Michael Olbrich <M.Olbrich at protonmail.com>

Citation (from within R, enter citation("MBECS")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MBECS")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MBECS")
MBECS introduction HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews BatchEffect, Microbiome, Normalization, QualityControl, ReportWriting, Software, Visualization
Version 1.16.0
In Bioconductor since BioC 3.15 (R-4.2) (4.5 years)
License Artistic-2.0
Depends R (>= 4.1)
Imports methods, magrittr, phyloseq, limma, lme4, lmerTest, pheatmap, rmarkdown, cluster, dplyr, ggplot2, gridExtra, ruv, sva, tibble, tidyr, vegan, stats, utils, Matrix
System Requirements
URL https://github.com/rmolbrich/MBECS
Bug Reports https://github.com/rmolbrich/MBECS/issues/new
See More
Suggests knitr, markdown, BiocStyle, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MBECS_1.16.0.tar.gz
Windows Binary (x86_64) MBECS_1.16.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) MBECS_1.16.0.tgz
macOS Binary (sonoma-arm64) MBECS_1.16.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/MBECS
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/MBECS
Bioc Package Browser https://code.bioconductor.org/browse/MBECS/
Package Short Url https://bioconductor.org/packages/MBECS/
Package Downloads Report Download Stats