Package: methrix
Title: Fast and efficient summarization of generic bedGraph files from
        Bisufite sequencing
Version: 1.25.0
Authors@R: c(
  person("Anand","Mayakonda", role = c("aut", "cre"), email = "anand_mt@hotmail.com", comment = c(ORCID = "0000-0003-1162-687X")),
  person("Reka","Toth", role = "aut", email = "r.toth@dkfz.de", comment = c(ORCID = "0000-0002-6096-1052")),
  person("Rajbir","Batra", role = "ctb"), person("Clarissa","Feuerstein-Akgöz", role = "ctb"),
  person("Joschka","Hey", role = "ctb"),
  person("Maximilian","Schönung", role = "ctb"),
  person("Pavlo","Lutsik", role = "ctb"))
Description: Bedgraph files generated by Bisulfite pipelines often come
        in various flavors. Critical downstream step requires
        summarization of these files into methylation/coverage
        matrices. This step of data aggregation is done by Methrix,
        including many other useful downstream functions.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: false
Depends: R (>= 3.6), data.table (>= 1.12.4), SummarizedExperiment
Imports: rtracklayer, DelayedArray, HDF5Array, BSgenome,
        DelayedMatrixStats, parallel, methods, ggplot2, S4Vectors,
        matrixStats, graphics, stats, utils, GenomicRanges, IRanges
RoxygenNote: 7.1.1
Suggests: knitr, rmarkdown, DSS, bsseq, plotly,
        BSgenome.Mmusculus.UCSC.mm9, MafDb.1Kgenomes.phase3.GRCh38,
        MafDb.1Kgenomes.phase3.hs37d5, BSgenome.Hsapiens.UCSC.hg19,
        GenomicScores, Biostrings, RColorBrewer, GenomeInfoDb, testthat
        (>= 2.1.0)
VignetteBuilder: knitr
biocViews: DNAMethylation, Sequencing, Coverage
URL: https://github.com/CompEpigen/methrix
BugReports: https://github.com/CompEpigen/methrix/issues
Config/pak/sysreqs: make libbz2-dev liblzma-dev libxml2-dev libssl-dev
        xz-utils zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2025-10-29 14:55:34 UTC
RemoteUrl: https://github.com/bioc/methrix
RemoteRef: HEAD
RemoteSha: 797afd5e3b0c16fc097d0fcdfa78626715ea4da4
NeedsCompilation: no
Packaged: 2026-03-05 08:36:10 UTC; root
Author: Anand Mayakonda [aut, cre] (ORCID:
    <https://orcid.org/0000-0003-1162-687X>),
  Reka Toth [aut] (ORCID: <https://orcid.org/0000-0002-6096-1052>),
  Rajbir Batra [ctb],
  Clarissa Feuerstein-Akgöz [ctb],
  Joschka Hey [ctb],
  Maximilian Schönung [ctb],
  Pavlo Lutsik [ctb]
Maintainer: Anand Mayakonda <anand_mt@hotmail.com>
Built: R 4.6.0; ; 2026-03-07 03:39:05 UTC; windows
