# Heterogeneity-Induced Pre-Processing tOol

## Documentation for package ‘HIPPO’ version 1.23.0

- DESCRIPTION file
- User guides, package vignettes and other documentation
- Package NEWS
- Package README

## Help Pages

%>% | re-export magrittr pipe operator
ensg_hgnc | A reference data frame that matches ENSG IDs to HGNC symbols
get_data_from_sce | Access data from SCE object
get_hippo | Access hippo object from SingleCellExperiment object.
get_hippo_diffexp | Return hippo_diffexp object
hippo | HIPPO's hierarchical clustering
hippo_diagnostic_plot | Conduct feature selection by computing test statistics for each gene
hippo_diffexp | HIPPO's differential expression
hippo_dimension_reduction | compute t-SNE or umap of each round of HIPPO
hippo_feature_heatmap | HIPPO's feature heatmap
hippo_pca_plot | visualize each round of hippo through t-SNE
hippo_tsne_plot | visualize each round of hippo through t-SNE
hippo_umap_plot | visualize each round of hippo through UMAP
nb_prob_zero | Expected zero proportion under Negative Binomial
pois_prob_zero | Expected zero proportion under Poisson
preprocess_heterogeneous | Preprocess UMI data without cell label so that each row contains information about each gene
preprocess_homogeneous | Preprocess UMI data with inferred or known labels
toydata | A sample single cell sequencing data subsetted from Zheng2017
zero_proportion_plot | visualize each round of hippo through zero proportion plot
zinb_prob_zero | Expected zero proportion under Negative Binomial