Package: gemini
Type: Package
Title: GEMINI: Variational inference approach to infer genetic
        interactions from pairwise CRISPR screens
Version: 1.25.0
Authors@R: c(
  person("Mahdi", "Zamanighomi", email = "mzamanig@broadinstitute.org", role = c('aut')),
  person("Sidharth", "Jain", email = "sidharthsjain@gmail.com", role = c('aut', 'cre'))
  )
Description: GEMINI uses log-fold changes to model sample-dependent and
        independent effects, and uses a variational Bayes approach to
        infer these effects. The inferred effects are used to score and
        identify genetic interactions, such as lethality and recovery.
        More details can be found in Zamanighomi et al. 2019 (in
        press).
Depends: R (>= 4.1.0)
License: BSD_3_clause + file LICENSE
Encoding: UTF-8
LazyData: false
RoxygenNote: 7.1.1
biocViews: Software, CRISPR, Bayesian, DataImport
BugReports: https://github.com/sellerslab/gemini/issues
Imports: dplyr, grDevices, ggplot2, magrittr, mixtools, scales,
        pbmcapply, parallel, stats, utils
Suggests: knitr, rmarkdown, testthat
VignetteBuilder: knitr
Config/pak/sysreqs: make libicu-dev libssl-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2025-10-29 14:52:58 UTC
RemoteUrl: https://github.com/bioc/gemini
RemoteRef: HEAD
RemoteSha: 37133b1e1361202441ab8f66f6423814a0e080f7
NeedsCompilation: no
Packaged: 2026-02-22 07:46:59 UTC; root
Author: Mahdi Zamanighomi [aut],
  Sidharth Jain [aut, cre]
Maintainer: Sidharth Jain <sidharthsjain@gmail.com>
Built: R 4.6.0; ; 2026-02-22 07:48:26 UTC; windows
