Package: HPiP
Type: Package
Title: Host-Pathogen Interaction Prediction
Version: 1.16.0
Authors@R: c(
    person("Matineh", "Rahmatbakhsh", ,"matinerb.94@gmail.com",c("aut","trl","cre")),
    person("Mohan", "Babu", ,"mohan.babu@uregina.ca", c("led")))
Description: HPiP (Host-Pathogen Interaction Prediction) uses an
        ensemble learning algorithm for prediction of host-pathogen
        protein-protein interactions (HP-PPIs) using structural and
        physicochemical descriptors computed from amino
        acid-composition of host and pathogen proteins.The proposed
        package can effectively address data shortages and data
        unavailability for HP-PPI network reconstructions. Moreover,
        establishing computational frameworks in that regard will
        reveal mechanistic insights into infectious diseases and
        suggest potential HP-PPI targets, thus narrowing down the range
        of possible candidates for subsequent wet-lab experimental
        validations.
Depends: R (>= 4.1)
Imports: dplyr (>= 1.0.6), httr (>= 1.4.2), readr, tidyr, tibble,
        utils, stringr, magrittr, caret, corrplot, ggplot2, pROC,
        PRROC, igraph, graphics, stats, purrr, grDevices, protr, MCL
License: MIT + file LICENSE
Encoding: UTF-8
URL: https://github.com/mrbakhsh/HPiP
BugReports: https://github.com/mrbakhsh/HPiP/issues
VignetteBuilder: knitr
Suggests: rmarkdown, colorspace, e1071, kernlab, ranger,
        SummarizedExperiment, Biostrings, randomForest, gprofiler2,
        gridExtra, ggthemes, BiocStyle, BiocGenerics, RUnit, tools,
        knitr
biocViews: Proteomics, SystemsBiology, NetworkInference,
        StructuralPrediction, GenePrediction, Network
RoxygenNote: 7.2.0
Config/pak/sysreqs: libglpk-dev libicu-dev libxml2-dev libssl-dev
        libx11-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2025-10-29 15:12:09 UTC
RemoteUrl: https://github.com/bioc/HPiP
RemoteRef: RELEASE_3_22
RemoteSha: 5ee7131ef44b54a5463a0718d8a48f0a063535dc
NeedsCompilation: no
Packaged: 2026-01-23 08:19:36 UTC; root
Author: Matineh Rahmatbakhsh [aut, trl, cre],
  Mohan Babu [led]
Maintainer: Matineh Rahmatbakhsh <matinerb.94@gmail.com>
Built: R 4.5.2; ; 2026-01-23 08:21:18 UTC; windows
