Package: awst
Title: Asymmetric Within-Sample Transformation
Version: 1.18.0
Authors@R: 
    c(person(given = "Davide",
                family = "Risso",
                role = c("aut", "cre", "cph"),
                email = "risso.davide@gmail.com",
                comment = c(ORCID = "0000-0001-8508-5012")),
        person(given = "Stefano",
               family = "Pagnotta",
               role = c("aut", "cph"),
               email = "smpagnotta@gmail.com",
               comment = c(ORCID = "0000-0002-8298-9777")))
Description: 
    We propose an Asymmetric Within-Sample Transformation (AWST)
    to regularize RNA-seq read counts and reduce the effect of noise
    on the classification of samples. AWST comprises two main steps:
    standardization and smoothing. These steps transform gene expression data to
    reduce the noise of the lowly expressed features, which suffer from
    background effects and low signal-to-noise ratio, and the influence of the
    highly expressed features, which may be the result of amplification bias
    and other experimental artifacts.
License: MIT + file LICENSE
Encoding: UTF-8
RoxygenNote: 7.1.1
URL: https://github.com/drisso/awst
BugReports: https://github.com/drisso/awst/issues
Imports: stats, methods, SummarizedExperiment
Suggests: airway, ggplot2, testthat, EDASeq, knitr, BiocStyle,
        RefManageR, sessioninfo, rmarkdown
biocViews: Normalization, GeneExpression, RNASeq, Software,
        Transcriptomics, Sequencing, SingleCell
VignetteBuilder: knitr
git_url: https://git.bioconductor.org/packages/awst
git_branch: RELEASE_3_22
git_last_commit: fa8583c
git_last_commit_date: 2025-10-29
Repository: Bioconductor 3.22
Date/Publication: 2025-10-29
NeedsCompilation: no
Packaged: 2025-10-30 02:35:45 UTC; biocbuild
Author: Davide Risso [aut, cre, cph] (ORCID:
    <https://orcid.org/0000-0001-8508-5012>),
  Stefano Pagnotta [aut, cph] (ORCID:
    <https://orcid.org/0000-0002-8298-9777>)
Maintainer: Davide Risso <risso.davide@gmail.com>
