Package: CONSTANd
Type: Package
Title: Data normalization by matrix raking
Version: 1.17.0
Date: 2020-10-30
Authors@R: c(person("Joris", "Van Houtven", email="joris.vanhoutven@uhasselt.be", role=c("aut","trl")),
			 person("Geert Jan", "Bex", email="geertjan.bex@uhasselt.be", role=c("trl")),
			 person("Dirk", "Valkenborg", email="dirk.valkenborg@uhasselt.be", role=c("aut", "cre")))
Description: Normalizes a data matrix `data` by raking (using the RAS method by Bacharach, see references) the Nrows by Ncols matrix such that the row means and column means equal 1. The result is a normalized data matrix `K=RAS`, a product of row mulipliers `R` and column multipliers `S` with the original matrix `A`. Missing information needs to be presented as `NA` values and not as zero values, because CONSTANd is able to ignore missing values when calculating the mean. Using CONSTANd normalization allows for the direct comparison of values between samples within the same and even across different CONSTANd-normalized data matrices.
License: file LICENSE
Encoding: UTF-8
biocViews: MassSpectrometry, Cheminformatics, Normalization,
        Preprocessing, DifferentialExpression, Genetics,
        Transcriptomics, Proteomics
NeedsCompilation: no
Depends: R (>= 4.1)
Suggests: BiocStyle, knitr, rmarkdown, tidyr, ggplot2, gridExtra,
        magick, Cairo, limma
SystemRequirements:
BugReports: https://github.com/PDiracDelta/CONSTANd/issues
URL: qcquan.net/constand
VignetteBuilder: knitr
git_url: https://git.bioconductor.org/packages/CONSTANd
git_branch: devel
git_last_commit: 4f7af02
git_last_commit_date: 2025-04-15
Repository: Bioconductor 3.22
Date/Publication: 2025-06-04
Packaged: 2025-06-04 22:14:09 UTC; biocbuild
Author: Joris Van Houtven [aut, trl],
  Geert Jan Bex [trl],
  Dirk Valkenborg [aut, cre]
Maintainer: Dirk Valkenborg <dirk.valkenborg@uhasselt.be>
Built: R 4.5.0; ; 2025-06-05 12:44:21 UTC; windows
