@article{Abdi,
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@article{Brown,
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@article{DeHaan,
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@article{Harrington,
  title={Analysis of Variance--Principal Component Analysis: A Soft Tool for Proteomic Discovery},
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  number={1},
  pages={118--127},
  year={2005},
  publisher={Elsevier}
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@Manual{ChemoSpec,
  title  = {\pkg{ChemoSpec}: Exploratory Chemometrics for Spectroscopy},
  author = {Bryan A Hanson},
  year   = {2012},
  note   = {\proglang{R}~package version~1.51-2},
  url    = {http://CRAN.R-project.org/package=ChemoSpec},
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@Manual{pls,
    title = {\pkg{pls}: Partial Least Squares and Principal Component Regression},
    author = {Bjørn-Helge Mevik and Ron Wehrens and Kristian Hovde Liland},
    year = {2011},
    note = {\proglang{R}~package version~2.3-0},
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  }

@article{Nueda,
  title={Discovering Gene Expression Patterns in Time Course Microarray Experiments by ANOVA--SCA},
  author={Nueda, M.J. and Conesa, A. and Westerhuis, J.A. and Hoefsloot, H.C.J. and Smilde, A.K. and Tal{\'o}n, M. and Ferrer, A.},
  journal={Bioinformatics},
  volume={23},
  number={14},
  pages={1792--1800},
  year={2007},
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@article{PradoLopez,
  title={Hypoxia Promotes Efficient Differentiation of Human Embryonic Stem Cells to Functional Endothelium},
  author={Prado-Lopez, S. and Conesa, A. and Armi{\~n}{\'a}n, A. and Mart{\'\i}nez-Losa, M. and Escobedo-Lucea, C. and Gandia, C. and Tarazona, S. and Melguizo, D. and Blesa, D. and Montaner, D. and others},
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  volume={28},
  number={3},
  pages={407--418},
  year={2010},
  publisher={Wiley Online Library}
}

@Manual{R,
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    author = {{R Development Core Team}},
    organization = {R Foundation for Statistical Computing},
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    year = {2012},
    note = {{ISBN} 3-900051-07-0},
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  }

@book{ShaweTaylor,
  title={Kernel Methods for Pattern Analysis},
  author={Shawe-Taylor, J. and Cristianini, N.},
  isbn={9780521813976},
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  year={2004},
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}

@article{Smilde,
  title={ANOVA-Simultaneous Component Analysis (ASCA): A New Tool for Analysing Designed Metabolomics Data},
  author={Smilde, A.K. and Jansen, J.J. and Hoefsloot, H.C.J. and Lamers, R.J.A.N. and Van Der Greef, J. and Timmerman, M.E.},
  journal={Bioinformatics},
  volume={21},
  number={13},
  pages={3043--3048},
  year={2005},
  publisher={Oxford University Press}
}

@Manual{limma,
    title = {\pkg{limma}: Linear Models for Microarray Data},
    author = {Smyth, Gordon K. and Ritchie, Matthew and Silver, Jeremy and James Wettenhall and Natalie Thorne and Mette Langaas and Egil Ferkingstad and Marcus Davy and Francois Pepin and Dongseok Choi and Davis McCarthy and Di Wu and Alicia Oshlack and Carolyn de Graaf and Yifang Hu and Wei Shi and Belinda Phipson.},
    year = {2011},
    note = {\proglang{R}~package version~3.12.1},
    url = {http://www.bioconductor.org/packages/2.10/bioc/html/limma.html}
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@article{Smyth,
  title={Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments.},
  author={Smyth, Gordon K.},
  journal={Statistical Applications in Genetics and Molecular Biology},
  volume={3},
  number={1},
  pages={Article 3},
  year={2004}
}

@article{Subramanian,
  title={Gene Set Enrichment Analysis: A Knowledge-Based Approach for Interpreting Genome-Wide Expression Profiles},
  author={Subramanian, A. and Tamayo, P. and Mootha, V.K. and Mukherjee, S. and Ebert, B.L. and Gillette, M.A. and Paulovich, A. and Pomeroy, S.L. and Golub, T.R. and Lander, E.S. and others},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={102},
  number={43},
  pages={15545--15550},
  year={2005},
  publisher={Proceedings of the National Academy of Sciences}
}

@article{Zwanenburg,
  title={ANOVA-Principal Component Analysis and ANOVA-Simultaneous Component Analysis: A Comparison},
  author={Zwanenburg, G. and Hoefsloot, H.C.J. and Westerhuis, J.A. and Jansen, J.J. and Smilde, A.K.},
  journal={Journal of Chemometrics},
  year={2011},
  volume={25},
  number={10},
  pages={561--567}
}

@article{GEO,
    author = {Edgar, Ron and Domrachev, Michael and Lash, Alex E.},
    doi = {10.1093/nar/30.1.207},
    issn = {1362-4962},
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    number = {1},
    pages = {207--210},
    pmid = {11752295},
    publisher = {Oxford University Press},
    title = {Gene Expression Omnibus: NCBI Gene Expression and Hybridization Array Data Repository},
    url = {http://dx.doi.org/10.1093/nar/30.1.207},
    volume = {30},
    year = {2002}
}

@Manual{lmdme,
    title = {\pkg{lmdme}: Linear Model Decomposition for Designed Multivariate Experiments},
    author = {Fresno, Crist\'{o}bal and Fern\'{a}ndez, Elmer Andr\'{e}s},
    year = {2013},
    note = {\proglang{R}~package version~1.2.1},
    url = {http://www.bioconductor.org/packages/release/bioc/html/lmdme.html}
 }

@Manual{stemHypoxia,
    title = {\pkg{stemHypoxia}: Differentiation of Human Embryonic Stem Cells Under Hypoxia Gene Expression Dataset by Prado-Lopez et al. (2010)},
    author = {Fresno, Crist\'{o}bal and Fern\'{a}ndez, Elmer Andr\'{e}s},
    year = {2013},
    note = {\proglang{R}~package version~0.99.3},
    url = {http://www.bioconductor.org/packages/release/data/experiment/html/stemHypoxia.html}
 }

@Article{Bioconductor,
    author = {Robert C Gentleman and Vincent J. Carey and Douglas M. Bates and {others}},
    title = {Bioconductor: Open Software Development for Computational Biology and Bioinformatics},
    journal = {Genome Biology},
    volume = {5},
    year = {2004},
    pages = {R80},
    url = {http://genomebiology.com/2004/5/10/R80},
}

@Article{lmdmeJSS,
    author = {Fresno, Crist{\'o}bal and M{\'o}nica G. Balzarini and Fern{\'a}ndez, Elmer Andr{\'e}s},
    title = {{lmdme}: Linear Models on Designed Multivariate Experiments in {R}},
    journal = {Journal of Statistical Software},
    year = {2014},
    volume = {56},
    number = {7},
    pages = {1--16},
    url = {http://www.jstatsoft.org/v56/i07/},
}

@article{Tarazona,
  title={Variable Selection for Multifactorial Genomic Data},
  author={Tarazona, S. and Prado-L{\'o}pez, S. and Dopazo, J. and Ferrer, A. and Conesa, A.},
  journal={Chemometrics and Intelligent Laboratory Systems},
  year={2012},
  volume={110},
  number = {1},
  pages={113--122},
  publisher={Elsevier}
}
