Changes in version 1.99.2 - gsePathway() now exposes eps and forwards extra arguments (...) to enrichit::gsea_gson(), matching the other GSEA wrappers in the family (2026-09-22, Tue, #47) - gsePathway() and nsePathway() now expose an explicit seed parameter for reproducible GSEA results, aligned with enrichit::gsea_gson(): set it to a number (or TRUE for a fixed default seed) to get identical results across runs; FALSE (default) draws a fresh seed on each run (2026-08-15, Fri) - prepareReactomeNetwork() is ~40x faster: the per-pathway conversion no longer round-trips through graphite::convertIdentifiers()/pathwayGraph() (whose per-call mapIds() overhead was hash/SQLite-bound and capped parallel scaling at ~4-5 effective cores). It now builds a single UNIPROT->Entrez map up front and converts the protein edges with vectorized lookups, keeping mclapply() parallelization over pathways. The resulting network is identical to the previous output (same nodes and edge values; only node ordering may differ). The default cores is now 1 (serial, ~40 s for human; options(mc.cores=...) or an explicit cores= still enables parallel) instead of detectCores() (2026-08-16, Sat) Changes in version 1.99.1 - nsePathway(): network-based set enrichment analysis (NSEA) on the Reactome reaction graph using Random Walk with Restart (2026-07-08, Wed) - bayes_reactome(): Bayesian term selection for compressing redundant Reactome pathway output via enrichit::bayes_enrich() (2026-07-08, Wed) - prepareReactomeNetwork(): utility to build and cache the Reactome reaction graph for reuse in nsePathway() (2026-07-08, Wed) - enrichPathway() and gsePathway() now accept a weight parameter for weighted ORA/GSEA (2026-07-08, Wed) - migrate caching from custom environment (reactome_env) to yulab.utils::with_cache(); delete get_Reactome_DATA(), getALLEG() (2026-07-08, Wed) - gson_Reactome() now caches the final GSON object directly, with data cleaning inlined (2026-07-08, Wed) Changes in version 1.56.0 - Bioconductor RELEASE_3_23 (2026-04-29, Wed) Changes in version 1.55.1 - use 'enrichit' as engine for enrichment analysis (2025-12-07, Sun) Changes in version 1.54.0 - Bioconductor RELEASE_3_22 (2025-11-01, Sat) Changes in version 1.52.0 - Bioconductor RELEASE_3_21 (2025-04-17, Thu) Changes in version 1.50.0 - Bioconductor (2024-10-30, Wed) Changes in version 1.49.1 - use yulab.utils::yulab_msg() for startup message (2024-07-26, Fri) Changes in version 1.48.0 - Bioconductor RELEASE_3_19 (2024-05-15, Wed) Changes in version 1.47.1 - Add a disclaimer in package Description to claim that this package is not affiliated with the Reactome team (2023-11-17, Fri) Changes in version 1.46.0 - Bioconductor RELEASE_3_18 (2023-10-25, Wed) Changes in version 1.44.0 - Bioconductor RELEASE_3_16 (2022-11-02, Wed) Changes in version 1.41.1 - add function gson_Reactome (2022-7-13, Wed) Changes in version 1.34.0 - Bioconductor 3.12 release (2020-10-28, Wed)