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sosta

This is the development version of sosta; for the stable release version, see sosta.

A package for the analysis of anatomical tissue structures in spatial omics data


Bioconductor version: Development (3.24)

sosta (Spatial Omics STructure Analysis) is a package for analyzing spatial omics data to explore tissue organization at the anatomical structure level. It reconstructs anatomically relevant structures based on molecular features or cell types. It further calculates a range of metrics at the structure level to quantitatively describe tissue architecture. The package is designed to integrate with other packages for the analysis of spatial omics data.

Author: Samuel Gunz [aut, cre] ORCID iD ORCID: 0000-0002-8909-0932 , Mark D. Robinson [aut, fnd]

Maintainer: Samuel Gunz <samuel.gunz at uzh.ch>

Citation (from within R, enter citation("sosta")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("sosta")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("sosta")
Overview of sosta HTML R Script
Reconstruction and analysis of pancreatic islets from IMC data HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Software, Spatial, Transcriptomics, Visualization
Version 1.5.1
In Bioconductor since BioC 3.21 (R-4.5) (1.5 years)
License GPL (>= 3) + file LICENSE
Depends R (>= 4.4.0)
Imports terra, sf, smoothr, spatstat.explore, spatstat.geom, SpatialExperiment, SingleCellExperiment, dplyr, ggplot2, patchwork, SummarizedExperiment, stats, rlang, parallel, EBImage, spatstat.random, S4Vectors
System Requirements
URL https://github.com/sgunz/sosta https://sgunz.github.io/sosta/
Bug Reports https://github.com/sgunz/sosta/issues
See More
Suggests knitr, rmarkdown, BiocStyle, ExperimentHub, lme4, lmerTest, ggfortify, tidyr, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me OSTA
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package sosta_1.5.1.tar.gz
Windows Binary (x86_64) sosta_1.5.1.zip
macOS Binary (big-sur-x86_64) sosta_1.5.1.tgz
macOS Binary (sonoma-arm64) sosta_1.5.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/sosta
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/sosta
Bioc Package Browser https://code.bioconductor.org/browse/sosta/
Package Short Url https://bioconductor.org/packages/sosta/
Package Downloads Report Download Stats