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qsea

This is the development version of qsea; for the stable release version, see qsea.

IP-seq data analysis and vizualization


Bioconductor version: Development (3.24)

qsea (quantitative sequencing enrichment analysis) was developed as the successor of the MEDIPS package for analyzing data derived from methylated DNA immunoprecipitation (MeDIP) experiments followed by sequencing (MeDIP-seq). However, qsea provides several functionalities for the analysis of other kinds of quantitative sequencing data (e.g. ChIP-seq, MBD-seq, CMS-seq and others) including calculation of differential enrichment between groups of samples.

Author: Matthias Lienhard [aut, cre] ORCID iD ORCID: 0000-0002-2549-3142 , Lukas Chavez [aut] ORCID iD ORCID: 0000-0002-8718-8848 , Ralf Herwig [aut] ORCID iD ORCID: 0000-0002-9335-1760

Maintainer: Matthias Lienhard <lienhard at molgen.mpg.de>

Citation (from within R, enter citation("qsea")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("qsea")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("qsea")
qsea HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews ChIPSeq, ChipOnChip, CopyNumberVariation, CpGIsland, DNAMethylation, DifferentialMethylation, Normalization, Preprocessing, QualityControl, Sequencing, Software, Visualization
Version 1.39.0
In Bioconductor since BioC 3.4 (R-3.3) (10 years)
License GPL-2
Depends R (>= 4.3)
Imports Biostrings, graphics, gtools, methods, stats, utils, HMMcopy, rtracklayer, BSgenome, GenomicRanges, Rsamtools, IRanges, limma, Seqinfo, BiocGenerics, grDevices, zoo, BiocParallel, S4Vectors
System Requirements
URL
See More
Suggests BSgenome.Hsapiens.UCSC.hg19, MEDIPSData, testthat, BiocStyle, knitr, rmarkdown, BiocManager, MASS
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me MEDIPSData
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package qsea_1.39.0.tar.gz
Windows Binary (x86_64) qsea_1.39.0.zip
macOS Binary (big-sur-x86_64) qsea_1.39.0.tgz
macOS Binary (sonoma-arm64) qsea_1.39.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/qsea
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/qsea
Bioc Package Browser https://code.bioconductor.org/browse/qsea/
Package Short Url https://bioconductor.org/packages/qsea/
Package Downloads Report Download Stats