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glycoTraitR

This is the development version of glycoTraitR; for the stable release version, see glycoTraitR.

Compute and analyze the glycan structrual traits from GPSM data


Bioconductor version: Development (3.24)

GlycoTraitR is an R package for analyzing glycoproteomics data, particularly glycopeptide-spectrum matches (GPSMs). It supports results generated by the pGlyco3 and Glyco-Decipher search engines. The package parses glycan structures, computes monosaccharide compositions and structural traits, and performs differential analysis of glycan heterogeneity. It constructs trait-by-PSM matrices stored in a SummarizedExperiment object, supports user-defined structural motifs, and provides visualization utilities for interpreting glycan trait changes.

Author: Bingyuan Zhang [aut, cre] ORCID iD ORCID: 0000-0002-4892-323X , Koichi Himori [aut], Yusuke Matsui [aut, fnd]

Maintainer: Bingyuan Zhang <zhang.bingyuan.w8 at f.mail.nagoya-u.ac.jp>

Citation (from within R, enter citation("glycoTraitR")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("glycoTraitR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("glycoTraitR")
Quick Start HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews MassSpectrometry, Proteomics, Software, Visualization
Version 1.1.0
In Bioconductor since BioC 3.23 (R-4.6) (< 6 months)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports igraph, SummarizedExperiment, pbapply, car, ggplot2, rlang
System Requirements
URL https://github.com/matsui-lab/glycoTraitR
Bug Reports https://github.com/matsui-lab/glycoTraitR/issues
See More
Suggests knitr, BiocStyle, rmarkdown, markdown, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package glycoTraitR_1.1.0.tar.gz
Windows Binary (x86_64) glycoTraitR_1.1.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) glycoTraitR_1.1.0.tgz
macOS Binary (sonoma-arm64) glycoTraitR_1.1.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/glycoTraitR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/glycoTraitR
Bioc Package Browser https://code.bioconductor.org/browse/glycoTraitR/
Package Short Url https://bioconductor.org/packages/glycoTraitR/
Package Downloads Report Download Stats