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dbSequence

This is the development version of dbSequence; to use it, please install the devel version of Bioconductor.

DuckDB-Backed Interface for Large-Scale Genomic Data


Bioconductor version: Development (3.24)

Provides a DuckDB-backed infrastructure for working with large-scale genomic data that exceeds available memory. Supports lazy evaluation of genomic ranges and efficient overlap queries. Integrates with Bioconductor classes (GRanges, BiocIO) and provides plyranges-compatible API.

Author: Edward C. Ruiz [aut, cre] ORCID iD ORCID: 0000-0002-9174-5387 , Ruben Dries [rev], National Human Genome Research Institute [fnd] (grant: 1R01HG014487-01)

Maintainer: Edward C. Ruiz <ecr7407 at gmail.com>

Citation (from within R, enter citation("dbSequence")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("dbSequence")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("dbSequence")
Data Ingestion HTML R Script
plyranges API HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Coverage, DataImport, DataRepresentation, Infrastructure, Sequencing, Software
Version 0.99.1
In Bioconductor since BioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.6.0)
Imports methods, duckdb, DBI, dbplyr, dplyr, glue, arrow, BiocIO, rtracklayer, Rsamtools, VariantAnnotation, dbProject, GenomicRanges, IRanges, rlang, cli, crayon
System Requirements
URL https://github.com/dbverse-org/dbSequence
Bug Reports https://github.com/dbverse-org/dbSequence/issues
See More
Suggests testthat (>= 3.0.0), SingleCellExperiment, scater, knitr, rmarkdown, BiocStyle, plyranges, microbenchmark
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
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Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package dbSequence_0.99.1.tar.gz
Windows Binary (x86_64) dbSequence_0.99.1.zip
macOS Binary (big-sur-x86_64) dbSequence_0.99.1.tgz
macOS Binary (sonoma-arm64) dbSequence_0.99.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/dbSequence
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/dbSequence
Bioc Package Browser https://code.bioconductor.org/browse/dbSequence/
Package Short Url https://bioconductor.org/packages/dbSequence/
Package Downloads Report Download Stats