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dStruct

This is the development version of dStruct; for the stable release version, see dStruct.

Identifying differentially reactive regions from RNA structurome profiling data


Bioconductor version: Development (3.24)

dStruct identifies differentially reactive regions from RNA structurome profiling data. dStruct is compatible with a broad range of structurome profiling technologies, e.g., SHAPE-MaP, DMS-MaPseq, Structure-Seq, SHAPE-Seq, etc. See Choudhary et al., Genome Biology, 2019 for the underlying method.

Author: Krishna Choudhary [aut, cre] ORCID iD ORCID: 0000-0002-7966-1527 , Sharon Aviran [aut] ORCID iD ORCID: 0000-0003-1872-9820

Maintainer: Krishna Choudhary <kchoudhary at ucdavis.edu>

Citation (from within R, enter citation("dStruct")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("dStruct")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("dStruct")
Differential RNA structurome analysis using `dStruct` HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Sequencing, Software, StatisticalMethod, StructuralPrediction
Version 1.19.0
In Bioconductor since BioC 3.14 (R-4.1) (5 years)
License GPL (>= 2)
Depends R (>= 4.1)
Imports zoo, ggplot2, purrr, reshape2, parallel, IRanges, S4Vectors, rlang, grDevices, stats, utils
System Requirements
URL https://github.com/dataMaster-Kris/dStruct
Bug Reports https://github.com/dataMaster-Kris/dStruct/issues
See More
Suggests BiocStyle, knitr, rmarkdown, tidyverse, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package dStruct_1.19.0.tar.gz
Windows Binary (x86_64) dStruct_1.19.0.zip
macOS Binary (big-sur-x86_64) dStruct_1.19.0.tgz
macOS Binary (sonoma-arm64) dStruct_1.19.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/dStruct
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/dStruct
Bioc Package Browser https://code.bioconductor.org/browse/dStruct/
Package Short Url https://bioconductor.org/packages/dStruct/
Package Downloads Report Download Stats