Bioconductor 3.22 Released

clusterProfiler

This is the development version of clusterProfiler; for the stable release version, see clusterProfiler.

A Universal Enrichment Tool for Interpreting Omics Data


Bioconductor version: Development (3.23)

A universal tool for interpreting functional characteristics of omics data. It supports Over-Representation Analysis (ORA) and Gene Set Enrichment Analysis (GSEA) for both coding and non-coding genomics data of thousands of species. It provides a unified and tidy interface to access, manipulate, and visualize enrichment results. A key capability is the simultaneous analysis and comparison of datasets from multiple treatments or time points. Furthermore, it integrates Large Language Model (LLM) capabilities to provide automated and insightful interpretation of enrichment results.

Author: Guangchuang Yu [aut, cre, cph] ORCID iD ORCID: 0000-0002-6485-8781 , Li-Gen Wang [ctb], Xiao Luo [ctb], Meijun Chen [ctb], Giovanni Dall'Olio [ctb], Wanqian Wei [ctb], Chun-Hui Gao [ctb] ORCID iD ORCID: 0000-0002-1445-7939

Maintainer: Guangchuang Yu <guangchuangyu at gmail.com>

Citation (from within R, enter citation("clusterProfiler")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("clusterProfiler")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("clusterProfiler")
clusterProfiler.html HTML
Reference Manual PDF
NEWS Text

Details

biocViews Annotation, Clustering, GO, GeneSetEnrichment, KEGG, MultipleComparison, Pathways, Reactome, Software, Visualization
Version 4.19.6
In Bioconductor since BioC 2.8 (R-2.13) (15 years)
License Artistic-2.0
Depends R (>= 4.2.0)
Imports AnnotationDbi, dplyr, enrichit (>= 0.1.1), enrichplot(>= 1.9.3), ggplot2, GO.db, GOSemSim(>= 2.27.2), gson (>= 0.0.7), httr, igraph, jsonlite, magrittr, methods, plyr, qvalue, rlang, stats, tidyr, utils, yulab.utils (>= 0.2.3)
System Requirements
URL https://yulab-smu.top/contribution-knowledge-mining/
Bug Reports https://github.com/YuLab-SMU/clusterProfiler/issues
See More
Suggests AnnotationHub, BiocManager, DOSE, fanyi (>= 0.1.0), ggtangle, readr, org.Hs.eg.db, quarto, testthat
Linking To
Enhances
Depends On Me
Imports Me bioCancer, CaMutQC, CBNplot, CEMiTool, CeTF, damidBind, debrowser, EasyCellType, epiregulon.extra, GDCRNATools, goSorensen, MetaPhOR, methylGSA, miRSM, miRspongeR, mitology, Moonlight2R, MoonlightR, mosdef, PanomiR, pathlinkR, Pigengene, ReducedExperiment, RFLOMICS, vsclust, recountWorkflow, DRviaSPCN, genekitr, PathwayVote, SurprisalAnalysis, tinyarray, XYomics
Suggests Me ChIPseeker, ClusterGVis, cola, DAPAR, DeeDeeExperiment, DOSE, enrichplot, EpiCompare, EpiMix, epiSeeker, GeDi, GeneTonic, GenomicSuperSignature, GeoTcgaData, ggkegg, GOSemSim, GRaNIE, GSEAmining, mastR, MesKit, MicrobiomeProfiler, ReactomePA, rrvgo, scFeatures, scGPS, scGraphVerse, TCGAbiolinks, tidybulk, org.Mxanthus.db, enrichit, ggpicrust2, grandR, ivolcano, OlinkAnalyze, ReporterScore, SRscore
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package clusterProfiler_4.19.6.tar.gz
Windows Binary (x86_64) clusterProfiler_4.19.3.zip
macOS Binary (big-sur-x86_64) clusterProfiler_4.19.2.tgz
macOS Binary (big-sur-arm64) clusterProfiler_4.19.6.tgz
macOS Binary (sonoma-arm64)
Source Repository git clone https://git.bioconductor.org/packages/clusterProfiler
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/clusterProfiler
Bioc Package Browser https://code.bioconductor.org/browse/clusterProfiler/
Package Short Url https://bioconductor.org/packages/clusterProfiler/
Package Downloads Report Download Stats