TPP2D
This is the development version of TPP2D; for the stable release version, see TPP2D.
Detection of ligand-protein interactions from 2D thermal profiles (DLPTP)
Bioconductor version: Development (3.24)
Detection of ligand-protein interactions from 2D thermal profiles (DLPTP), Performs an FDR-controlled analysis of 2D-TPP experiments by functional analysis of dose-response curves across temperatures.
Author: Nils Kurzawa [aut, cre], Holger Franken [aut], Simon Anders [aut], Wolfgang Huber [aut], Mikhail M. Savitski [aut]
Maintainer: Nils Kurzawa <nilskurzawa at gmail.com>
citation("TPP2D")):
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.
Installation
To install this package, start R (version "4.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")
BiocManager::install("TPP2D")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("TPP2D")| Introduction to TPP2D for 2D-TPP analysis | HTML | R Script |
| Reference Manual | ||
| NEWS | Text |
Details
| biocViews | DataImport, Proteomics, Software |
| Version | 1.29.0 |
| In Bioconductor since | BioC 3.9 (R-3.6) (7.5 years) |
| License | GPL-3 |
| Depends | R (>= 3.6.0), stats, utils, dplyr, methods |
| Imports | ggplot2, tidyr, foreach, doParallel, openxlsx, stringr, RCurl, parallel, MASS, BiocParallel, limma |
| System Requirements | |
| URL | http://bioconductor.org/packages/TPP2D |
| Bug Reports | https://support.bioconductor.org/ |
See More
| Suggests | knitr, testthat, rmarkdown, BiocStyle |
| Linking To | |
| Enhances | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | TPP2D_1.29.0.tar.gz |
| Windows Binary (x86_64) | TPP2D_1.29.0.zip (64-bit only) |
| macOS Binary (big-sur-x86_64) | TPP2D_1.29.0.tgz |
| macOS Binary (sonoma-arm64) | TPP2D_1.29.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/TPP2D |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/TPP2D |
| Bioc Package Browser | https://code.bioconductor.org/browse/TPP2D/ |
| Package Short Url | https://bioconductor.org/packages/TPP2D/ |
| Package Downloads Report | Download Stats |