Bioc2026 Registration Open!

TPP

This is the development version of TPP; for the stable release version, see TPP.

Analyze thermal proteome profiling (TPP) experiments


Bioconductor version: Development (3.24)

Analyze thermal proteome profiling (TPP) experiments with varying temperatures (TR) or compound concentrations (CCR).

Author: Dorothee Childs [cre, aut], Nils Kurzawa [aut], Holger Franken [aut], Carola Doce [aut], Mikhail Savitski [aut], Wolfgang Huber [aut]

Maintainer: Dorothee Childs <d.childs at posteo.de>

Citation (from within R, enter citation("TPP")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("TPP")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews ImmunoOncology, MassSpectrometry, Proteomics, Software
Version 3.41.0
In Bioconductor since BioC 3.1 (R-3.2) (11.5 years)
License Artistic-2.0
Depends R (>= 3.4), Biobase, dplyr, magrittr, tidyr
Imports biobroom, data.table, doParallel, foreach, futile.logger, ggplot2, grDevices, gridExtra, grid, knitr, limma, MASS, mefa, nls2, openxlsx (>= 2.4.0), parallel, plyr, purrr, RColorBrewer, RCurl, reshape2, rlang, rmarkdown, splines, stats, stringr, tibble, utils, VennDiagram, VGAM
System Requirements
URL
See More
Suggests BiocStyle, testthat
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me Rtpca
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64) TPP_3.41.0.zip
macOS Binary (big-sur-x86_64) TPP_3.41.0.tgz
macOS Binary (sonoma-arm64) TPP_3.41.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/TPP
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/TPP
Package Short Url https://bioconductor.org/packages/TPP/
Package Downloads Report Download Stats