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SanityR

This is the development version of SanityR; for the stable release version, see SanityR.

R/Bioconductor interface to the Sanity model gene expression analysis


Bioconductor version: Development (3.24)

a Bayesian normalization procedure derived from first principles. Sanity estimates expression values and associated error bars directly from raw unique molecular identifier (UMI) counts without any tunable parameters.

Author: Teo Sakel [aut, cre] ORCID iD ORCID: 0000-0001-9946-9498 , MCIU/AEI [fnd] (ROR: <https://ror.org/05r0vyz12>, DOI: 10.13039/501100011033)

Maintainer: Teo Sakel <teo at intelligentbiodata.com>

Citation (from within R, enter citation("SanityR")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("SanityR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SanityR")
Normalizing scRNA-seq data with Sanity HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Bayesian, GeneExpression, Normalization, SingleCell, Software
Version 1.3.0
In Bioconductor since BioC 3.22 (R-4.5) (1 year)
License GPL (>= 3)
Depends
Imports Rcpp, BiocGenerics, BiocParallel, MatrixGenerics, methods, S4Vectors, scuttle, SingleCellExperiment, SummarizedExperiment
System Requirements
URL https://github.com/TeoSakel/SanityR
Bug Reports https://github.com/TeoSakel/SanityR/issues
See More
Suggests BiocStyle, knitr, rmarkdown, testthat (>= 3.0.0), scater, Rtsne
Linking To Rcpp
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package SanityR_1.3.0.tar.gz
Windows Binary (x86_64) SanityR_1.3.0.zip
macOS Binary (big-sur-x86_64) SanityR_1.3.0.tgz
macOS Binary (sonoma-arm64) SanityR_1.3.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/SanityR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/SanityR
Bioc Package Browser https://code.bioconductor.org/browse/SanityR/
Package Short Url https://bioconductor.org/packages/SanityR/
Package Downloads Report Download Stats