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SETA

This is the development version of SETA; for the stable release version, see SETA.

Single Cell Ecological Taxonomic Analysis


Bioconductor version: Development (3.24)

Tools for compositional and other sample-level ecological analyses and visualizations tailored for single-cell RNA-seq data. SETA includes functions for taxonomizing celltypes, normalizing data, performing statistical tests, and visualizing results. Several tutorials are included to guide users and introduce them to key concepts. SETA is meant to teach users about statistical concepts underlying ecological analysis methods so they can apply them to their own single-cell data.

Author: Kyle Kimler [aut, cre] ORCID iD ORCID: 0000-0003-4735-9064 , Marc Elosua-Bayes [aut]

Maintainer: Kyle Kimler <kkimler at broadinstitute.org>

Citation (from within R, enter citation("SETA")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("SETA")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SETA")
Comparing samples with SETA HTML R Script
Introduction to SETA ecological transforms and sample-level latent spaces HTML R Script
Multi-Resolution Compositional Analysis in scRNA-seq: Reference Frames with SETA HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews DataRepresentation, DimensionReduction, GeneExpression, Normalization, RNASeq, SingleCell, Software, StatisticalMethod, SystemsBiology, Transcriptomics, Visualization
Version 1.3.0
In Bioconductor since BioC 3.22 (R-4.5) (1 year)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports dplyr, MASS, Matrix, SingleCellExperiment(>= 1.30.1), stats, tidygraph, rlang, utils
System Requirements
URL https://github.com/kkimler/SETA
Bug Reports https://github.com/kkimler/SETA/issues
See More
Suggests BiocStyle, caret, glmnet, corrplot, ggplot2, ggraph, knitr, methods, patchwork, reshape2, rmarkdown, SeuratObject, Seurat, SummarizedExperiment, TabulaMurisSenisData, tidyr, tidytext, testthat (>= 3.0.0)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package SETA_1.3.0.tar.gz
Windows Binary (x86_64) SETA_1.3.0.zip
macOS Binary (big-sur-x86_64) SETA_1.3.0.tgz
macOS Binary (sonoma-arm64) SETA_1.3.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/SETA
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/SETA
Bioc Package Browser https://code.bioconductor.org/browse/SETA/
Package Short Url https://bioconductor.org/packages/SETA/
Package Downloads Report Download Stats