REBET

This is the development version of REBET; for the stable release version, see REBET.

The subREgion-based BurdEn Test (REBET)

Bioconductor version: Development (3.24)

There is an increasing focus to investigate the association between rare variants and diseases. The REBET package implements the subREgion-based BurdEn Test which is a powerful burden test that simultaneously identifies susceptibility loci and sub-regions.

Author: Bill Wheeler [cre], Bin Zhu [aut], Lisa Mirabello [ctb], Nilanjan Chatterjee [ctb]

Maintainer: Bill Wheeler <wheelerb at imsweb.com>

Citation (from within R, enter citation("REBET")):

Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("REBET")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("REBET")

REBET Vignette	PDF	R Script
Reference Manual	PDF
NEWS	Text

Need some help? Ask on the Bioconductor Support site!

Details

biocViews	SNP, Software, VariantAnnotation
Version	1.31.0
In Bioconductor since	BioC 3.8 (R-3.5) (8 years)
License	GPL-2
Depends	ASSET
Imports	stats, utils
System Requirements
URL

Suggests	RUnit, BiocGenerics
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report	Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	REBET_1.31.0.tar.gz
Windows Binary (x86_64)	REBET_1.31.0.zip
macOS Binary (big-sur-x86_64)	REBET_1.31.0.tgz
macOS Binary (sonoma-arm64)	REBET_1.31.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/REBET
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/REBET
Bioc Package Browser	https://code.bioconductor.org/browse/REBET/
Package Short Url	https://bioconductor.org/packages/REBET/
Package Downloads Report	Download Stats