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IntEREst

This is the development version of IntEREst; for the stable release version, see IntEREst.

Intron-Exon Retention Estimator


Bioconductor version: Development (3.24)

This package performs Intron-Exon Retention analysis on RNA-seq data (.bam files).

Author: Ali Oghabian <Ali.Oghabian at Helsinki.Fi>, Dario Greco <dario.greco at helsinki.fi>, Mikko Frilander <Mikko.Frilander at helsinki.fi>

Maintainer: Ali Oghabian <Ali.Oghabian at Helsinki.Fi>

Citation (from within R, enter citation("IntEREst")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("IntEREst")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("IntEREst")
IntEREst, Intron Exon Retention Estimator HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Alignment, AlternativeSplicing, Coverage, DifferentialExpression, DifferentialSplicing, ImmunoOncology, Normalization, RNASeq, Sequencing, Software
Version 1.37.0
In Bioconductor since BioC 3.5 (R-3.4) (9.5 years)
License GPL-2
Depends R (>= 3.5.0), GenomicRanges, Rsamtools, SummarizedExperiment, edgeR, S4Vectors, GenomicFiles
Imports seqLogo, Biostrings, GenomicFeatures(>= 1.39.4), txdbmaker, IRanges, seqinr, graphics, grDevices, stats, utils, grid, methods, DBI, RMariaDB, GenomicAlignments, BiocParallel, BiocGenerics, DEXSeq, DESeq2
System Requirements
URL
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Suggests clinfun, knitr, rmarkdown, BSgenome.Hsapiens.UCSC.hg19
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Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package IntEREst_1.37.0.tar.gz
Windows Binary (x86_64) IntEREst_1.37.0.zip
macOS Binary (big-sur-x86_64) IntEREst_1.37.0.tgz
macOS Binary (sonoma-arm64) IntEREst_1.37.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/IntEREst
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/IntEREst
Bioc Package Browser https://code.bioconductor.org/browse/IntEREst/
Package Short Url https://bioconductor.org/packages/IntEREst/
Package Downloads Report Download Stats