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HEM

This is the development version of HEM; for the stable release version, see HEM.

Heterogeneous error model for identification of differentially expressed genes under multiple conditions


Bioconductor version: Development (3.24)

This package fits heterogeneous error models for analysis of microarray data

Author: HyungJun Cho <hcho at virginia.edu> and Jae K. Lee <jaeklee at virginia.edu>

Maintainer: HyungJun Cho <hcho at virginia.edu>

Citation (from within R, enter citation("HEM")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("HEM")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HEM")
HEM Overview PDF
Reference Manual PDF

Details

biocViews DifferentialExpression, Microarray, Software
Version 1.85.0
In Bioconductor since BioC 1.7 (R-2.2) (21 years)
License GPL (>= 2)
Depends R (>= 2.1.0)
Imports Biobase, grDevices, stats, utils
System Requirements
URL http://www.healthsystem.virginia.edu/internet/hes/biostat/bioinformatics/
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HEM_1.85.0.tar.gz
Windows Binary (x86_64) HEM_1.85.0.zip
macOS Binary (big-sur-x86_64) HEM_1.85.0.tgz
macOS Binary (sonoma-arm64) HEM_1.85.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/HEM
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/HEM
Bioc Package Browser https://code.bioconductor.org/browse/HEM/
Package Short Url https://bioconductor.org/packages/HEM/
Package Downloads Report Download Stats