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DOtools

This is the development version of DOtools; for the stable release version, see DOtools.

Convenient functions to streamline your single cell data analysis workflow


Bioconductor version: Development (3.24)

This package provides functions for creating various visualizations, convenient wrappers, and quality-of-life utilities for single cell experiment objects. It offers a streamlined approach to visualize results and integrates different tools for easy use.

Author: Mariano Ruz Jurado [aut, cre] ORCID iD ORCID: 0000-0001-5354-5336 , David Rodriguez Morales [aut] ORCID iD ORCID: 0000-0002-1819-6991 , David John [aut] ORCID iD ORCID: 0000-0003-3217-5449 , DFG SFB 1366, Project B04 [fnd], DFG SFB 1531, Project 456687919 [fnd]

Maintainer: Mariano Ruz Jurado <ruzjurado at med.uni-frankfurt.de>

Citation (from within R, enter citation("DOtools")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("DOtools")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DOtools")
Quality control of sc/snRNA-seq HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Annotation, Clustering, GeneExpression, QualityControl, RNASeq, SingleCell, Software, Visualization, WorkflowStep
Version 1.3.5
In Bioconductor since BioC 3.22 (R-4.5) (1 year)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports Seurat (>= 5.2.0), SeuratObject (>= 5.1.0), ggplot2 (>= 3.5.0), ggpubr (>= 0.6.0), ggtext (>= 0.1.2), ggalluvial (>= 0.12.5), ggrastr (>= 1.0.2), tidyverse (>= 2.0.0), reshape2 (>= 1.4.4), dplyr (>= 1.1.4), tidyr (>= 1.3.1), rstatix (>= 0.7.2), cowplot (>= 1.1.3), reticulate (>= 1.41.0.1), zellkonverter(>= 1.16.0), progress (>= 1.2.3), ggiraphExtra (>= 0.3.0), grid (>= 4.4.3), SCpubr (>= 2.0.2), DropletUtils(>= 1.26.0), scCustomize (>= 3.0.1), openxlsx (>= 4.2.8), tibble (>= 3.2.1), scDblFinder(>= 1.20.0), ggcorrplot (>= 0.1.4.1), DESeq2(>= 1.48.1), glmGamPoi(>= 1.24.0), enrichR (>= 3.4), cli (>= 3.6.5), curl (>= 6.3.0), magrittr (>= 2.0.3), Matrix (>= 1.7.3), purrr (>= 1.0.4), rlang (>= 1.1.6), scales (>= 1.4.0), SingleCellExperiment(>= 1.30.1), S4Vectors(>= 0.46.0), basilisk(>= 1.20.0), FNN (>= 1.1.4.1), ks, methods, stats, utils
System Requirements
URL https://marianoruzjurado.github.io/DOtools/
Bug Reports https://github.com/MarianoRuzJurado/DOtools/issues
See More
Suggests SummarizedExperiment, knitr, kableExtra, pkgdown, RefManageR, BiocStyle, roxygen2, httr, magick, rmarkdown, assertthat, plyr, rsvg, scran, scater, igraph, sessioninfo, testthat (>= 3.0.0), leidenbase (>= 0.1.36), mockery
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DOtools_1.3.5.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) DOtools_1.3.5.tgz
macOS Binary (sonoma-arm64) DOtools_1.3.5.tgz
Source Repository git clone https://git.bioconductor.org/packages/DOtools
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DOtools
Bioc Package Browser https://code.bioconductor.org/browse/DOtools/
Package Short Url https://bioconductor.org/packages/DOtools/
Package Downloads Report Download Stats