Bioc2026 Registration Open!

BERT

This is the development version of BERT; for the stable release version, see BERT.

High Performance Data Integration for Large-Scale Analyses of Incomplete Omic Profiles Using Batch-Effect Reduction Trees (BERT)


Bioconductor version: Development (3.24)

Provides efficient batch-effect adjustment of data with missing values. BERT orders all batch effect correction to a tree of pairwise computations. BERT allows parallelization over sub-trees.

Author: Yannis Schumann [aut, cre] ORCID iD ORCID: 0000-0002-2379-200X , Simon Schlumbohm [aut] ORCID iD ORCID: 0000-0002-0083-5142

Maintainer: Yannis Schumann <yannis.schumann at desy.de>

Citation (from within R, enter citation("BERT")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("BERT")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("BERT")
BERT-Vignette HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews BatchEffect, ExperimentalDesign, Preprocessing, QualityControl, Software
Version 1.9.0
In Bioconductor since BioC 3.19 (R-4.4) (2.5 years)
License GPL-3
Depends R (>= 4.3.0)
Imports cluster, comprehenr, foreach (>= 1.5.2), invgamma, iterators (>= 1.0.14), janitor (>= 2.2.0), limma(>= 3.46.0), logging (>= 0.10-108), sva(>= 3.38.0), SummarizedExperiment, methods, BiocParallel
System Requirements
URL https://github.com/HSU-HPC/BERT/
Bug Reports https://github.com/HSU-HPC/BERT/issues
See More
Suggests testthat (>= 3.0.0), knitr, rmarkdown, BiocStyle
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package BERT_1.9.0.tar.gz
Windows Binary (x86_64) BERT_1.9.0.zip
macOS Binary (big-sur-x86_64) BERT_1.9.0.tgz
macOS Binary (sonoma-arm64) BERT_1.9.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/BERT
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/BERT
Bioc Package Browser https://code.bioconductor.org/browse/BERT/
Package Short Url https://bioconductor.org/packages/BERT/
Package Downloads Report Download Stats